Affordable Access

Comprehensive analysis of the beta-myosin heavy chain gene in 389 unrelated patients with hypertrophic cardiomyopathy.

Authors
  • Van Driest, Sara L
  • Jaeger, Michele A
  • Ommen, Steve R
  • Will, Melissa L
  • Gersh, Bernard J
  • Tajik, A Jamil
  • Ackerman, Michael J
Type
Published Article
Journal
Journal of the American College of Cardiology
Publisher
Elsevier
Publication Date
Aug 04, 2004
Volume
44
Issue
3
Pages
602–610
Identifiers
PMID: 15358028
Source
Medline
License
Unknown

Abstract

In this setting, HCM patients with MYH7 were diagnosed at a younger age and had more hypertrophy, but they had no greater frequency of sudden death among first-degree relatives. Although these associations may prove useful for targeted gene screening, caution should be exercised in terms of using pathogenic status in risk stratification.

Report this publication

Statistics

Seen <100 times