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The complexing of lysozyme with poly C and other homopolymers.

Authors
  • Preiss, J W
Type
Published Article
Journal
Biophysical journal
Publication Date
Nov 01, 1968
Volume
8
Issue
11
Pages
1201–1210
Identifiers
PMID: 5696207
Source
Medline
License
Unknown

Abstract

Lysozyme forms very large complexes with poly C, in acetate buffer solutions (pH 5.4), when the ratio of lysozyme to poly C concentration is 3/2. When this is less than 3/8 there is virtually no complexing, as evidenced by the low light-scattering power of such mixtures. At such relatively high poly C concentrations, the addition of pancreatic ribonuclease causes both the intensity and dissymmetry of scattering to rise to very high values after which time the intensity falls exponentially with time and with very little change in dissymmetry. Other homopolymers also form largest complexes with lysozyme at characteristic concentration ratios.

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