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Complementation analysis of linked circadian clock mutants of Neurospora crassa.

Authors
  • Feldman, J F
  • Hoyle, M N
Type
Published Article
Journal
Genetics
Publication Date
Jan 01, 1976
Volume
82
Issue
1
Pages
9–17
Identifiers
PMID: 129346
Source
Medline
License
Unknown

Abstract

A fourth mutant of Neurospora crassa, designated frq-4, has been isolated in which the period length of the circadian conidiation rhythm is shortened to 19. +/- 0.3 hours. This mutant is tightly linked to the three previously isolated frq mutants, and all four map to the right arm of linkage group VII about 10 map units from the centromere. Complementation tests suggest, but do not prove, that all four mutations are allelic, since each of the four mutants is co-dominant with the frq+ allel--i.e., heterokaryons have period lengths intermediate between the mutant and wild-type--and since heterokaryons between pairs of mutants also have period lengths intermediate between those of the two mutants.

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