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Comparison of twice-daily vs once-daily deferasirox dosing in a gerbil model of iron cardiomyopathy.

Authors
  • Otto-Duessel, Maya
  • Aguilar, Michelle
  • Nick, Hanspeter
  • Moats, Rex
  • Wood, John C
Type
Published Article
Journal
Experimental Hematology
Publisher
Elsevier
Publication Date
Jul 01, 2007
Volume
35
Issue
7
Pages
1069–1073
Identifiers
PMID: 17588475
Source
Medline
License
Unknown

Abstract

Daily divided dosing of deferasirox changes the relative cardiac and liver iron chelation profile compared with daily single dosing, trading improvements in cardiac iron elimination for less-effective hepatic chelation.

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