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Comparison of three commercial assays for the quantification of HIV-1 RNA in plasma from individuals infected with different HIV-1 subtypes.

Authors
  • Chew, C B
  • Herring, B L
  • Zheng, F
  • Browne, C
  • Saksena, N K
  • Cunningham, A L
  • Dwyer, D E
Type
Published Article
Journal
Journal of Clinical Virology
Publisher
Elsevier
Publication Date
Oct 01, 1999
Volume
14
Issue
2
Pages
87–94
Identifiers
PMID: 10588451
Source
Medline
License
Unknown

Abstract

These studies confirm that commercial HIV-1 load assays vary in their ability to quantify different HIV-1 subtypes. This may be more apparent with individual patient samples than with 'spiked' panels. This variability emphasizes that it is preferable for patient samples to be tested with the same assay, and care should be taken where infection with unusual subtypes is suspected.

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