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Comparison of serum antibodies to pneumolysin with those to pneumococcal capsular polysaccharides in children with acute otitis media.

Authors
  • Virolainen, A
  • Jero, J
  • Chattopadhyay, P
  • Karma, P
  • Eskola, J
  • Leinonen, M
Type
Published Article
Journal
The Pediatric infectious disease journal
Publication Date
Feb 01, 1996
Volume
15
Issue
2
Pages
128–133
Identifiers
PMID: 8822285
Source
Medline
License
Unknown

Abstract

Serum antibodies to pneumolysin can be detected at an earlier age than those to the capsular polysaccharides. However, a seroconversion is rare and therefore of no diagnostic value. The presence of serum IgG to the pneumococcal capsular polysaccharides seems beneficial in the prevention of pneumococcal otitis.

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