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Comparison of nitric oxide level in Behçet's disease patients with or without psychiatric comorbidity.

Authors
  • Kalenderoglu, Aysun1
  • Yilmaz, Sedat2
  • Oner, Ramazan Ilyas3
  • Orum, Mehmet Hamdi4
  • Karadag, Ayse Sevgi5
  • 1 Department of Psychiatry, Adiyaman University Faculty of Medicine , Adiyaman , Turkey. , (Turkey)
  • 2 Department of Biochemistry, Adiyaman University Faculty of Medicine , Adiyaman , Turkey. , (Turkey)
  • 3 Department of Internal Medicine, Adiyaman University Faculty of Medicine , Adiyaman , Turkey. , (Turkey)
  • 4 Psychiatry, Kahta State Hospital , Adiyaman , Turkey. , (Turkey)
  • 5 Department of Ophthalmology, Adiyaman University Faculty of Medicine , Adiyaman , Turkey. , (Turkey)
Type
Published Article
Journal
Journal of immunoassay & immunochemistry
Publication Date
Jan 01, 2019
Volume
40
Issue
5
Pages
502–514
Identifiers
DOI: 10.1080/15321819.2019.1646659
PMID: 31339439
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Both Behçet's disease (BD) and major depressive disorder (MDD) are diseases associated with nitric oxide (NO). We hypothesized that the comorbidity of MDD affects the levels of NO in BD. In this study, we investigate whether there was a difference in NO levels among BD patients with accompanying MDD, BD patients with no depressive symptoms and healthy control group. There was a significant difference in NO levels among BD and control group (P < 0.05). Also, there was a significant difference between the BD group with MDD and BD group without psychiatric comorbidity in terms of NO levels (P < 0.05). This study is interesting as it demonstrates that accompanying psychiatric comorbidity puts an additional NO burden on the shoulders of BD patients.

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