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Comparison of nifedipine with a new calcium channel blocker, flordipine, in exercise-induced asthma.

Authors
  • Gordon, E H
  • Wong, S C
  • Klaustermeyer, W B
Type
Published Article
Journal
The Journal of asthma : official journal of the Association for the Care of Asthma
Publication Date
Jan 01, 1987
Volume
24
Issue
5
Pages
261–265
Identifiers
PMID: 3327854
Source
Medline
License
Unknown

Abstract

Four patients with documented exercise-induced asthma (EIA) were pretreated orally in random, double-blind fashion with the calcium channel blockers nifedipine 20 mg and flordipine 25 and 50 mg and placebo, then subjected to exercise challenge on a cycloergometer. Each patient served as his own control, undergoing exercise challenge with the different pretreatments on 4 separate days. No statistically significant protection from EIA was found with either nifedipine or flordipine.

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