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A comparison of FLT to FDG PET/CT in the early assessment of chemotherapy response in stages IB-IIIA resectable NSCLC.

Authors
  • Crandall, John P1
  • Tahari, Abdel K2
  • Juergens, Rosalyn A3
  • Brahmer, Julie R4
  • Rudin, Charles M5
  • Esposito, Giuseppe6
  • Subramaniam, Deepa S7
  • Knopp, Michael V8
  • Hall, Nathan C9
  • Gajwani, Prateek10
  • Leal, Jeffrey P11
  • Lodge, Martin A11
  • O, Joo H12
  • Gabrielson, Edward W13
  • Shankar, Lalitha K14
  • Wahl, Richard L15, 16
  • 1 Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd, Campus Box 8131, St. Louis, MO, 63110, USA.
  • 2 Medical Imaging Department, King Fahad Specialist Hospital, P.O. Box 15215, Dammam, 31444-34, Saudi Arabia.
  • 3 Juravinski Cancer Centre, McMaster University, 699 Concession Street, Fourth, Hamilton, Ontario, L8V 5C2, Canada.
  • 4 Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, 1650 Orleans St, CRB I Room G-94, Baltimore, MD, 21287, USA.
  • 5 Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, 633 3rd Ave, New York, NY, 10017, USA.
  • 6 Department of Radiology, Georgetown University Hospital, 3800 Reservoir Road NW CCC Bldg., Washington, DC, 20007, USA.
  • 7 Department of Medicine, Georgetown University Hospital, 3800 Reservoir Road NW LCCC Bldg., Second Floor Pod B, Washington, DC, 20007, USA.
  • 8 Department of Radiology, The Ohio State University, Wexner Medical Center, 395 W. 12th Ave., Room 430, Columbus, OH, 43210, USA.
  • 9 Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 116 Donner, HUP 3400 Spruce Street, Philadelphia, PA, 19104, USA.
  • 10 The Johns Hopkins Wilmer Eye Institute, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Baltimore, MD, 21287, USA.
  • 11 The Russell H. Morgan Department of Radiology, Johns Hopkins University School of Medicine, Nelson B1-160, 600 N. Wolfe St., Baltimore, MD 21287, USA.
  • 12 Department of Nuclear Medicine, Seoul St. Mary's Hospital, Catholic Medical Center, Seocho-gu, Banpo-daero 222, Seoul, 06591, Korea.
  • 13 Department of Pathology, Johns Hopkins University School of Medicine, 1550 Orleans Street, 304 CRB II, Baltimore, MD, 21287, USA.
  • 14 National Cancer Institute, 6130 Executive Boulevard, MSC 7412, Bethesda, MD, 20892, USA.
  • 15 Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd, Campus Box 8131, St. Louis, MO, 63110, USA. [email protected]
  • 16 The Russell H. Morgan Department of Radiology, Johns Hopkins University School of Medicine, Nelson B1-160, 600 N. Wolfe St., Baltimore, MD 21287, USA. [email protected]
Type
Published Article
Journal
EJNMMI research
Publication Date
December 2017
Volume
7
Issue
1
Pages
8–8
Identifiers
DOI: 10.1186/s13550-017-0258-3
PMID: 28102506
Source
Medline
Keywords
License
Unknown

Abstract

Fractional decrease in FDG SULmax from baseline to post-cycle 1 imaging was significantly different between anatomic responders and non-responders, while percentage changes in FLT SULmax were not significantly different between these groups over the same period of time.

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