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Comparison of effects of quinidine and dihydroquinidine on canine heart.

Authors
  • Balazs, T
  • Herman, E
  • Atkinson, J
Type
Published Article
Journal
Journal of pharmaceutical sciences
Publication Date
Oct 01, 1978
Volume
67
Issue
10
Pages
1355–1357
Identifiers
PMID: 702278
Source
Medline
License
Unknown

Abstract

Various cardiac effects of quinidine and dihydroquinidine were tested in isolated dog hearts and in vivo in dogs. No significant differences were found in the negative inotropic, chronotropic, and dromotropic effects. Dihydroquinidine was more potent than quinidine in decreasing coronary arterial pressure.

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