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Comparison of configurations of a four-column simulated moving bed process by multi-objective optimization

Authors
  • Kawajiri, Yoshiaki1
  • Biegler, Lorenz T.1
  • 1 Carnegie Mellon University, Department of Chemical Engineering, 5000 Forbes Ave., Pittsburgh, PA, 15213, USA , Pittsburgh (United States)
Type
Published Article
Journal
Adsorption
Publisher
Springer US
Publication Date
Nov 09, 2007
Volume
14
Issue
2-3
Pages
433–442
Identifiers
DOI: 10.1007/s10450-007-9074-9
Source
Springer Nature
Keywords
License
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Abstract

Configurations of a four-column simulated moving bed chromatographic process are investigated by multi-objective optimization. Various existing column configurations are compared through a multi-objective optimization problem. Furthermore, an approach based on an SMB superstructure is applied to find novel configurations which have been found to outperform the standard SMB configuration. An efficient numerical optimization technique is applied to the mathematical model of the SMB process. It has been confirmed that although the optimal configuration highly depends on the purity requirement, the superstructure approach is able to find the most efficient configuration without exploring various existing configurations.

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