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Comparison of composite indices with global synovitis score on ultrasound for detecting remission

Authors
  • Olmez, Merve Ozata1
  • Gunal, Esen Kasapoglu2
  • Ureyen, Sibel Bakirci3
  • Keskin, Havva2
  • Ozturk, Ayse Bilge4
  • Yeter, Gokce5
  • Cobanoglu, Erim5
  • Aydin, Sibel Zehra6
  • 1 Istanbul Medeniyet University School of Medicine, Department of Internal Medicine, Istanbul, Turkey , Istanbul (Turkey)
  • 2 Istanbul Medeniyet University, Division of Rheumatology, Istanbul, Turkey , Istanbul (Turkey)
  • 3 University of Ottawa, Division of Rheumatology, Ottawa, Canada , Ottawa (Canada)
  • 4 Koc University, Division of Allergy and Immunology, Istanbul, Turkey , Istanbul (Turkey)
  • 5 Koc University, School of Medicine, Istanbul, Turkey , Istanbul (Turkey)
  • 6 University of Ottawa, Division of Rheumatology, Ottawa Hospital Research Institute, 1967 Riverside Drive, Ottawa, ON, K1H 7W9, Canada , Ottawa (Canada)
Type
Published Article
Journal
Clinical Rheumatology
Publisher
Springer-Verlag
Publication Date
Nov 27, 2017
Volume
37
Issue
4
Pages
1111–1114
Identifiers
DOI: 10.1007/s10067-017-3925-x
Source
Springer Nature
Keywords
License
Yellow

Abstract

We aimed to compare composite indices with Ultrasound Global Synovitis Score (GLOESS) for remission in rheumatoid arthritis (RA). RA patients in remission according to the clinician were investigated with Disease Activity Score28 (DAS28), Clinical Disease Activity Index (CDAI), Simplified Disease Activity Index (SDAI), and RAPID-3 (Routine Assessment of Patient Index Data 3). Ultrasonography was performed using the GLOESS scores. Patients in CDAI-remission had lower GLOESS (median (IQR), 5(3–9.75) vs 7(4–11.75), p = 0.048) with a similar trend in SDAI (5(3–9.25) vs 7(4–11.25), p = 0.064). This was not observed with DAS28-CRP and RAPID3. Our results show that CDAI is superior to other indices to assess remission in RA.

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