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A comparison of bolus insulin dose errors based on results of a clinical trial of five blood glucose monitoring systems.

Authors
  • Pardo, Scott1
  • 1 Ascensia Diabetes Care, Valhalla, NY 10595, USA.
Type
Published Article
Journal
Therapeutic Delivery
Publisher
"Future Science, LTD"
Publication Date
Dec 01, 2019
Volume
10
Issue
12
Pages
793–799
Identifiers
DOI: 10.4155/tde-2019-0047
PMID: 31789119
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Aim: Inaccurate blood glucose monitoring system (BGMS) results may lead to insulin dosing errors and adverse clinical outcomes. Results & methodology: This post-hoc analysis used a model to estimate the bolus insulin dose error associated with each of the five BGMSs, for a hypothetical person with diabetes (assuming a standardized meal and target blood glucose of 100 mg/dl). Differences in dose-error distribution between BGMSs were statistically tested. The 95% dose-error range for each BGMS was (insulin units): CONTOUR®PLUS, -1.1-0.7; Accu-Chek® Active, -2.4-0.7; Accu-Chek® Performa, -2.9-0.8; FreeStyle Freedom, from -5.5 to -0.5; OneTouch® SelectSimple™, -4.1-3.0. Conclusion: The CONTOUR®PLUS BGMS was associated with a statistically significantly smaller model-estimated median bolus insulin dose-error and dosing error range, compared with the other BGMSs.

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