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Comparison of the analytical and operational performance of two viral nucleic acid test blood screening systems: Procleix Tigris and cobas s 201.

Authors
  • Assal, Azzedine
  • Barlet, Valérie
  • Deschaseaux, Marie
  • Dupont, Isabelle
  • Gallian, Pierre
  • Guitton, Cathy
  • Morel, P
  • David, Bernard
  • De Micco, Philippe
Type
Published Article
Journal
Transfusion
Publication Date
Feb 01, 2009
Volume
49
Issue
2
Pages
289–300
Identifiers
DOI: 10.1111/j.1537-2995.2008.01965.x
PMID: 19000230
Source
Medline
License
Unknown

Abstract

Tigris ID-NAT format was significantly more sensitive than cobas s 201 MP-NAT in detecting HCV RNA and HIV RNA dilution panels, but despite the 1:6 dilution factor in s 201 the difference in sensitivity was not significant for some of the HBV genotype panels. Both NAT systems demonstrated acceptable operational performance, but for routine use further improvement in system reliability is desirable.

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