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Comparative study on the inhibitory effect of rimantadine on the reproduction of epidemic strains of influenza A virus H3N2 and H1N1.

Authors
  • Pushkarskaya, N L
  • Lvov, N D
  • Kochemasova, Z N
Type
Published Article
Journal
Acta virologica
Publication Date
Sep 01, 1981
Volume
25
Issue
5
Pages
319–321
Identifiers
PMID: 6118052
Source
Medline
License
Unknown

Abstract

The sensitivity to rimantadine of the reproduction of influenza virus A/Texas/1/77 (H3N2) and A (H1N1) isolates Nos 897, 778 and 782, isolated from patients during an epidemic influenza outbreak in Moscow in the winter of 1977/1978 was compared. A (H3N2) virus proved to be more sensitive than the A (H1N1) viruses tested, as manifested by decreases of the infectious titre in ovo and of the haemagglutinin titre in MDCK cells.

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