Affordable Access

[Comparative study of the fate of fluorofur and 5-fluorouracil in the organism].

Authors
  • Giller, S A
  • Meĭren, D V
  • Khagi, Kh B
  • Koptelova, M N
  • Shafro, E A
Type
Published Article
Journal
Voprosy onkologii
Publication Date
Jan 01, 1975
Volume
21
Issue
9
Pages
84–88
Identifiers
PMID: 1189367
Source
Medline
License
Unknown

Abstract

Fluorofur (FT) is slowly splitted in tissues releasing free 5-FU. The duration of stay in the organism of 5-FU formed from FT is longer than that of 5-FU administered solely. Moreover, FT does not result in the formation of such high 5-FU concentrations, as observed while using 5-FU itself. It seems to account for an insignificant toxicity of FT and its greater efficacy in treatment of malignant tumors.

Report this publication

Statistics

Seen <100 times