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Comparative study designs and what they show.

Authors
Type
Published Article
Journal
Respiratory Medicine
0954-6111
Publisher
Elsevier
Publication Date
Volume
94 Suppl D
Identifiers
PMID: 11003175
Source
Medline
License
Unknown

Abstract

Normally an increase in lung deposition leads to an improved clinical effect. An increase in clinical effect should be substantial (two-fold or greater) in order to be detected even in carefully conducted clinical trials. Further studies are needed in order to define the best clinical study designs with which to detect differences between different inhalers.

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