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[Comparative study of the changes in the EEG and cholinesterase activity in experimental Dipterex poisoning].

Authors
  • Khinkova, L
  • Kaloianova, F
  • Dimov, S
  • Atsev, E
Type
Published Article
Journal
Problemi na khigienata
Publication Date
Jan 01, 1975
Volume
1
Pages
39–44
Identifiers
PMID: 1236006
Source
Medline
License
Unknown

Abstract

A systematic study is conducted on cats, poisoned with the organophosphorus insecticide Dipterex. The changes in spontaneous and induced cortical activity along with those in serum and erythrocyte cholinesterase after intraperitoneal and intramuscular injection of Dipterex are investigated. Against the background of lowered cholinesterase activity, recorded in all the experiments , the changes in EEG appear to be discrete and inconstant. Uron single treatment with Dipterex, desynchronization prevails in the spontaneous EEG, whereas in the responses induced by light stimulants an increase of delayed negative potentiale prevails. Upon repeated Dipterex introduction, theta-like waves appear, associated with activation of paroxysmal manifestations existing in advance. Finally, the correlation between changes in cholinesterase activity and EEG is discussed.

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