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[A comparative morphological study of homo- and heterotopic neural transplants].

Authors
  • Otellin, V A
  • Petrova, E S
Type
Published Article
Journal
Morfologii︠a︡ (Saint Petersburg, Russia)
Publication Date
Jan 01, 1996
Volume
109
Issue
2
Pages
12–16
Identifiers
PMID: 8963409
Source
Medline
License
Unknown

Abstract

A comparative study of the development of neocortex embryonal anlage was carried out using light and electron microscopy in 15 days Wistar-line rat embryo after its transplantation into the brain and disturbed sciatic nerve of mature rats. Homotopic transplants contained twice more neurons than heterotopic ones 30 days later. Unlike to intracerebral transplants, in grafts developing in the nerve, there forms a multilayer lining from ependymocytes on the border with recipient tissue. Microenvironment was suggested to influence the realization of the transferred cells precursors histoblastic properties.

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