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Comparative In Vitro Activity of Ceftobiprole against Staphylococci Displaying Normal and Small-Colony Variant Phenotypes

Authors
  • Christof von Eiff
  • Alexander W. Friedrich
  • Karsten Becker
  • Georg Peters
Publisher
American Society for Microbiology
Publication Date
Oct 01, 2005
Source
PMC
Keywords
License
Unknown

Abstract

The antistaphylococcal activity of ceftobiprole was compared with those of cefuroxime, linezolid, and moxifloxacin by using the agar dilution method. Apart from three strains with small-colony variant phenotypes, all Staphylococcus aureus isolates tested were inhibited by ≤2 μg/ml of ceftobiprole. This compound exhibited an excellent antistaphylococcal activity, comparable to that of linezolid.

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