Affordable Access

[Comparative bactericidal kinetics of ciprofloxacin, ofloxacin and pefloxacin alone and in combination against strains of group D Streptococcus].

Authors
Type
Published Article
Journal
Pathologie Biologie
0369-8114
Publisher
Elsevier
Publication Date
Volume
36
Issue
5
Pages
403–409
Identifiers
PMID: 3136422
Source
Medline
License
Unknown

Abstract

Killing curves method was used to study bactericidal activity of the three quinolones, alone and in combination with penicillin, amoxicillin, fosfomycin, netilmicin, vancomycin against six isolates of enterococci. Alone, ofloxacin showed the most initial bactericidal effect but ciprofloxacin was the most frequently bactericidal without any regrowth in 24 hours. The combinations with beta-lactams and netilmicin were sometimes synergistic in 24 hours; fosfomycin increased initial bactericidal effect.

Statistics

Seen <100 times