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[Comparative analysis of efficacy of certain neuroprotectors in ischemic stroke].

Authors
  • Skorokhodov, A P
  • Dudina, A A
  • Kolesnikova, E A
  • Koron, A E
  • Kobantsev, Iu A
  • Sedova, A A
Type
Published Article
Journal
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
Publication Date
Jan 01, 2006
Volume
Suppl 17
Pages
52–56
Identifiers
PMID: 18193579
Source
Medline
License
Unknown

Abstract

Cortexin, nootropil and cerebrolysin have been used as neuroprotective medications in the acute period of ischemic stroke (IS). Clinical efficacy of cortexin and nootropil has been compared in 2 therapeutic series in 35 patients and that of cortexin and cerebrolysin--in 45 patients. The efficacy was assessed using several clinical and psychometric scales with statistical processing of the results. The data obtained suggest that in patients with moderate IS the drugs exert a similar and rather marked effect which was stronger comparing to the treatment without these drugs. At the same time, a domestic neuroprotector cortexin has some advantages, especially with regard to the absence of side-effects and "price-dose-therapeutic effect" criterion.

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