Affordable Access

Comorbidity and co-transmission of alcoholism, anxiety and depression.

Authors
  • Merikangas, K R
  • Risch, N J
  • Weissman, M M
Type
Published Article
Journal
Psychological medicine
Publication Date
Feb 01, 1994
Volume
24
Issue
1
Pages
69–80
Identifiers
PMID: 8208896
Source
Medline
License
Unknown

Abstract

This paper applies data from a family study of depression to assess patterns of comorbidity and co-transmission of alcoholism, anxiety disorder, and major depression. We found that all three disorders were strongly transmissible; however, alcoholism demonstrated the greatest degree of familial aggregation. The pairwise associations among depression, anxiety and alcoholism indicated that the traits are co-transmitted in families, especially depression and anxiety. Individual associations between traits (or comorbidity) were entirely explained by transmitted (perhaps genetic) agents, because the correlations between traits due to random environment were not significant. These findings have important implications for treatment, psychiatric nosology, and aetiological investigations of these conditions.

Report this publication

Statistics

Seen <100 times