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The commensal skin microbiota triggers type I IFN–dependent innate repair responses in injured skin

Authors
  • Di Domizio, Jeremy1
  • Belkhodja, Cyrine1
  • Chenuet, Pauline2
  • Fries, Anissa1
  • Murray, Timothy1
  • Mondéjar, Paula Marcos1
  • Demaria, Olivier1
  • Conrad, Curdin1
  • Homey, Bernhard3
  • Werner, Sabine4
  • Speiser, Daniel E.1
  • Ryffel, Bernhard2, 5
  • Gilliet, Michel1
  • 1 CHUV University Hospital, University of Lausanne, Lausanne, Switzerland , Lausanne (Switzerland)
  • 2 UMR 7355 CNRS-University of Orleans, Orleans, France , Orleans (France)
  • 3 Medical Faculty, Heinrich-Heine-University, Duesseldorf, Germany , Duesseldorf (Germany)
  • 4 ETH Zurich, Institute of Molecular Health Sciences, Zurich, Switzerland , Zurich (Switzerland)
  • 5 University of Cape Town, and South Africa Medical Research Council, Cape Town, South Africa , Cape Town (South Africa)
Type
Published Article
Journal
Nature Immunology
Publisher
Springer Nature
Publication Date
Jul 13, 2020
Volume
21
Issue
9
Pages
1034–1045
Identifiers
DOI: 10.1038/s41590-020-0721-6
Source
Springer Nature
License
Yellow

Abstract

Gilliet and colleagues demonstrate that skin wound healing occurs through the coordinated action of plasmacytoid dendritic cells, chemokines and skin microbiota.

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