Affordable Access

deepdyve-link
Publisher Website

Combined effects of tDCS over the left DLPFC and gaze-contingent training on attention mechanisms of emotion regulation in low-resilient individuals.

Authors
  • Sanchez-Lopez, Alvaro1
  • De Raedt, Rudi2
  • Puttevils, Louise3
  • Koster, Ernst H W2
  • Baeken, Chris4
  • Vanderhasselt, Marie-Anne5
  • 1 Department of Experimental Clinical and Health Psychology, Ghent University, Belgium; Department of Personality, Evaluation and Psychological Treatment, Complutense University of Madrid, Spain. Electronic address: [email protected] , (Belgium)
  • 2 Department of Experimental Clinical and Health Psychology, Ghent University, Belgium. , (Belgium)
  • 3 Department of Head and Skin, Ghent University, Belgium. , (Belgium)
  • 4 Department of Head and Skin, Ghent University, Belgium; Department of Psychiatry University Hospital (UZBrussel), Brussels, Belgium; Department of Electrical Engineering, University of Technology, Eindhoven, the Netherlands. , (Belgium)
  • 5 Department of Experimental Clinical and Health Psychology, Ghent University, Belgium; Department of Head and Skin, Ghent University, Belgium. , (Belgium)
Type
Published Article
Journal
Progress in neuro-psychopharmacology & biological psychiatry
Publication Date
Jun 08, 2021
Volume
108
Pages
110177–110177
Identifiers
DOI: 10.1016/j.pnpbp.2020.110177
PMID: 33189857
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Low resilience is characterized by impairments in attention and emotion regulation mechanisms that depend on prefrontal cortical activity. The aim of this study was to test whether transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex (DLPFC) can augment the effectiveness of a new computerized mouse-based (gaze)contingent training (MCAT) to improve attention and emotion regulation processes (improved reappraisal, reduced rumination) in individuals reporting low resilience levels. The study used a full-factorial between-subject design combining active and sham MCAT and tDCS interventions. One hundred participants reporting low resilience levels were randomly assigned to receive either a single session of: tDCS with sham MCAT treatment (tDCS group), MCAT with sham tDCS (MCAT group), a combination of tDCS and MCAT (combined group), or sham tDCS and sham MCAT (control group). Transfer to attention regulation, reappraisal success, and state rumination was evaluated using an eye-tracking disengagement task and an emotion regulation paradigm, respectively. MCAT, either alone or combined with tDCS, resulted in improved attention regulation. Furthermore, the group receiving combined MCAT and tDCS also showed some evidence of increased reappraisal ability and reduced rumination. MCAT in combination with left DLPFC neuromodulation has potential to maximize transfer to emotion regulation capacities and to promote resilience. Copyright © 2020 Elsevier Inc. All rights reserved.

Report this publication

Statistics

Seen <100 times