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Combination of gamma-interferon with TRAIL and cisplatin or etoposide induces apoptosis in human neuroblastoma cell line SH-SY5Y.

Authors
Type
Published Article
Journal
Chinese Medical Sciences Journal
1001-9294
Publisher
Chinese Medical Sciences Journal
Publication Date
Volume
22
Issue
1
Pages
38–43
Identifiers
PMID: 17441316
Source
Medline
License
Unknown

Abstract

IFNgamma could sensitize SH-SY5Y cells to TRAIL-induced apoptosis and this may be realized by the up-regulation of Caspase 8. Cisplatin and etoposide could enhance the killing effect of TRAIL on SH-SY5Y cells.

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