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A Combination of Allogeneic Stem Cells Promotes Cardiac Regeneration.

Authors
  • Natsumeda, Makoto1
  • Florea, Victoria1
  • Rieger, Angela C1
  • Tompkins, Bryon A2
  • Banerjee, Monisha N2
  • Golpanian, Samuel2
  • Fritsch, Julia1
  • Landin, Ana Marie1
  • Kashikar, Nilesh D3
  • Karantalis, Vasileios1
  • Loescher, Viky Y1
  • Hatzistergos, Kostas E1
  • Bagno, Luiza1
  • Sanina, Cristina1
  • Mushtaq, Muzammil1
  • Rodriguez, Jose1
  • Rosado, Marcos1
  • Wolf, Ariel1
  • Collon, Kevin1
  • Vincent, Louis1
  • And 6 more
  • 1 Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, Florida.
  • 2 Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, Florida; Department of Surgery, University of Miami Miller School of Medicine, Miami, Florida.
  • 3 Department of Pathology, University of Miami Miller School of Medicine, Miami, Florida.
  • 4 Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, Florida; Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida.
  • 5 Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida.
  • 6 Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, Florida; Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida. Electronic address: [email protected]
Type
Published Article
Journal
Journal of the American College of Cardiology
Publication Date
Nov 14, 2017
Volume
70
Issue
20
Pages
2504–2515
Identifiers
DOI: 10.1016/j.jacc.2017.09.036
PMID: 29145950
Source
Medline
Keywords
License
Unknown

Abstract

ACCT demonstrates synergistic effects to enhance cardiac regeneration and left ventricular functional recovery in a swine model of chronic ischemic cardiomyopathy without adverse immunologic reaction. Clinical translation to humans is warranted.

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