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Colorectal cancer update. Prevention, screening, treatment, and surveillance for high-risk groups.

Authors
Type
Published Article
Journal
The Medical clinics of North America
Publication Date
Volume
84
Issue
5
Identifiers
PMID: 11026923
Source
Medline

Abstract

Great advances have been made in understanding the cause and molecular genesis of colorectal cancer. The disease can be prevented by a healthful diet and lifestyle or by resecting the precursor of most of these cancers, the advanced adenomatous polyp. Screening the average-risk population plus special surveillance for high-risk groups now is recommended by evidence-based guidelines. Surgery is highly curative for patients without distant metastases, and adjuvant therapy improves survival in selected patients with advanced cancers.

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