Collecting a set of psoriasis family material through a patient organisation; clinical characterisation and presence of additional disorders

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Collecting a set of psoriasis family material through a patient organisation; clinical characterisation and presence of additional disorders

Publisher
BioMed Central
Publication Date
Oct 14, 2005
Source
PMC
Keywords
Disciplines
  • Medicine
License
Unknown

Abstract

1471-5945-5-10.fm ral ss BioMed CentBMC Dermatology Open AcceResearch article Collecting a set of psoriasis family material through a patient organisation; clinical characterisation and presence of additional disorders Annica Inerot*1, Charlotta Enerbäck1, Fredrik Enlund2, Tommy Martinsson2, Lena Samuelsson2, Jan Wahlström2 and Gunnar Swanbeck1 Address: 1Department of Dermatology, Sahlgrenska University Hospital/Sahlgrenska, SE-413 45 Göteborg, Sweden and 2Department of Clinical Genetics, Sahlgrenska University Hospital/Ostra, SE-416 85 Göteborg, Sweden Email: Annica Inerot* - [email protected]; Charlotta Enerbäck - [email protected]; Fredrik Enlund - [email protected]; Tommy Martinsson - [email protected]; Lena Samuelsson - [email protected]; Jan Wahlström - [email protected]; Gunnar Swanbeck - [email protected] * Corresponding author Abstract Background: The aim of the present study was to describe the clinical characteristics of a population of psoriatics sampled from a patient organisation and not from hospitals or out-patient clinics. Furthermore, we wanted to compare siblings with and without psoriasis regarding the occurrence of other diseases. Methods: At the end of 1991, we initiated a project which aimed to study genetic factors leading to psoriasis. Firstly, we sent questionnaires to all the members of the Swedish Psoriasis Association. We then examined 1,217 individuals (570 with psoriasis) from 310 families, in their homes in the southern part of Sweden. All the available family members were examined clinically and asked about the course of the skin disease and the occurrence of other diseases. The eight hundred members of the proband generation were divided into two groups, with or without psoriasis, and their clinical features were compared. Results: Most individuals in this study population had a mild form of psoriasis. The siblings with psoriasis had joint complaints significantly

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