2018), which aimed to explore associations between mixtures of air pollutants and other environmental variables with adverse birth outcomes by using an innovative data mining approach. The project was built on interdisciplinary and user knowledge participation with embedded evaluation framework of its collaborative process. We describe the collaborative process, the benefits and challenges encountered, and provide insights from our experience. We identified that interdisciplinary research requires time and investment in building relationships, continuous learning, and engagement to build bridges between disciplines towards co-production, discovery, and knowledge translation. Learning from interdisciplinary collaborative research experiences can facilitate future research in the challenging field of environmental health.