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Cold-inducible RNA binding protein (CIRP), a novel XTcf-3 specific target gene regulates neural development in Xenopus.

Authors
  • van Venrooy, Stephanie
  • Fichtner, Dagmar
  • Kunz, Martin
  • Wedlich, Doris
  • Gradl, Dietmar
Type
Published Article
Journal
BMC Developmental Biology
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Jan 01, 2008
Volume
8
Pages
77–77
Identifiers
DOI: 10.1186/1471-213X-8-77
PMID: 18687117
Source
Medline
License
Unknown

Abstract

Distinct steps in neural development are differentially regulated by individual Lef/Tcfs. For proper development of the anterior brain XTcf-3 and the Tcf-subtype specific target XCIRP appear indispensable. Thus, regulation of anterior neural development, at least in part, depends on mRNA stabilization by the novel XTcf-3 target gene XCIRP.

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