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Cognitive impairment in human chronic Chagas' disease.

Authors
  • Mangone, C A
  • Sica, R E
  • Pereyra, S
  • Genovese, O
  • Segura, E
  • Riarte, A
  • Sanz, O P
  • Segura, M
Type
Published Article
Journal
Arquivos de Neuro-Psiquiatria
Publisher
SciELO
Publication Date
Jun 01, 1994
Volume
52
Issue
2
Pages
200–203
Identifiers
PMID: 7826247
Source
Medline
License
Unknown

Abstract

Chagasic patients showed lower MMSE scores (p < .004), poor orientation (p < .004), and attention (p < .007). Lower WMS MQ were associated with CCD (Chi2 5.9; p < .01; Fisher test p < .02). Lower WAIS IQ were associated with CCD (Chi2 6.3, p < .01; Fisher test p < .01) being the digit symbol (p < .03), picture completion (p < .03), picture arrangement (p < .01) and object assembly (p < .03) subtests the most affected. The impairment in non-verbal reasoning, speed of information processing, problem solving, learning and sequencing observed in chronic Chagas disease patients resembles the cognitive dysfunction associated with white matter disease.

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