Affordable Access

Cognitive impairment in children with hemoglobin SS sickle cell disease: relationship to MR imaging findings and hematocrit.

Authors
  • Steen, R Grant
  • Miles, Mark A
  • Helton, Kathleen J
  • Strawn, Susan
  • Wang, Winfred
  • Xiong, Xiaoping
  • Mulhern, Raymond K
Type
Published Article
Journal
AJNR. American journal of neuroradiology
Publication Date
Mar 01, 2003
Volume
24
Issue
3
Pages
382–389
Identifiers
PMID: 12637286
Source
Medline
License
Unknown

Abstract

Focal brain injury, revealed by MR imaging, is associated with cognitive impairment, but our data suggest that diffuse brain injury may also contribute to impairment. These findings show that impairment is multifactorial and suggest that chronic brain hypoxia is part of the pathophysiology of sickle cell disease.

Report this publication

Statistics

Seen <100 times