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Clinicopathologic features of solid pseudopapillary pancreatic neoplasms in an Eastern Caribbean population.

Authors
  • Cawich, Shamir O1
  • Ledesma, Zulema2
  • Sampath, Lian3
  • Sandy, Sherisse4
  • 1 1 Consultant Surgeon, St. Augustine Campus, 37612 University of the West Indies, St. Augustine , Trinidad and Tobago. , (Trinidad & Tobago)
  • 2 2 Consultant Pathologist, St. Augustine Campus, 37612 University of the West Indies, St. Augustine , Trinidad and Tobago. , (Trinidad & Tobago)
  • 3 3 Surgical Resident, St. Augustine Campus, 37612 University of the West Indies, St. Augustine , Trinidad and Tobago. , (Trinidad & Tobago)
  • 4 4 Pathology Resident, St. Augustine Campus, 37612 University of the West Indies, St. Augustine , Trinidad and Tobago. , (Trinidad & Tobago)
Type
Published Article
Journal
Tropical Doctor
Publisher
SAGE Publications
Publication Date
Jul 01, 2018
Volume
48
Issue
3
Pages
224–227
Identifiers
DOI: 10.1177/0049475517744961
PMID: 29198177
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Pancreatic solid pseudopapillary neoplasms (SPNs) are uncommon lesions across the globe. Their incidence is unknown in the Caribbean. This retrospective study sought to document the clinicopathologic features of pancreatic SPNs in an Eastern Caribbean population. We examined data from the hospital records of all patients with SPN in Trinidad and Tobago, finding 11 cases over five years, equating to an incidence of 0.17 cases per 100,000 population per year. The lesions occurred in girls and young women at a mean age of 25 years, with a propensity for those of Afro-Caribbean descent. Poor prognostic factors (histologic invasion of the capsule, lymphovascular invasion, spindle cells, anaplastic cells and/or excessive mitotic figures) were present in 82% at the time of diagnosis. These tumours are uncommon in our population, and since most have poor prognostic features at diagnosis, we advocate an aggressive surgical approach.

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