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Clinical utility of selective molecular genotyping for diagnosis of partial hydatidiform mole; a retrospective study from a regional trophoblastic disease unit.

Authors
  • Fisher, Rosemary A1
  • Tommasi, Anna1
  • Short, Dee1
  • Kaur, Baljeet1
  • Seckl, Michael J1
  • Sebire, Neil J2
  • 1 Trophoblastic Disease Unit, Charing Cross Hospital, Imperial College, London, UK.
  • 2 Department of Histopathology, Great Ormond Street Hospital, London, UK.
Type
Published Article
Journal
Journal of Clinical Pathology
Publisher
BMJ
Publication Date
Nov 01, 2014
Volume
67
Issue
11
Pages
980–984
Identifiers
DOI: 10.1136/jclinpath-2014-202517
PMID: 25078332
Source
Medline
Keywords
License
Unknown

Abstract

Molecular genotyping allows definitive diagnosis of PHM for cases in which specialist histopathology review remains equivocal. While this approach provides definite diagnosis it is considerably more expensive than a pragmatic management approach of human chorionic gonadotrophin surveillance in all such cases.

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