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Clinical significance of coexisting antitopoisomerase I and anticentromere antibodies in patients with systemic sclerosis: a EUSTAR group-based study.

Authors
  • Heijnen, Ingmar A F M
  • Foocharoen, C
  • Bannert, Bettina
  • Carreira, Patricia E
  • Caporali, Roberto
  • Smith, Vanessa
  • Kumánovics, Gábor
  • Becker, Mike O
  • Vanthuyne, Marie
  • Simsek, Ismail
  • Bocelli-Tyndall, Chiara
  • Walker, Ulrich A
Type
Published Article
Journal
Clinical and experimental rheumatology
Publication Date
Jan 01, 2013
Volume
31
Issue
2 Suppl 76
Pages
96–102
Identifiers
PMID: 23101460
Source
Medline
License
Unknown

Abstract

Coexistence of ATA and ACA can be found at low prevalence in SSc. The clinical features of double-positive patients are not clearly dissimilar to those of patients harbouring only ATA. The data do not support a direct involvement of these antibodies in the pathogenesis of established SSc, but may lack statistical power.

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