Several years of study of senestopathy combined with subdepressive affective disorders in 38 patients with sluggish schizophrenia enabled the authors to describe the peculiarities of the natural history of these signs. The complicating senestopathy most frequently alternated with the periods of tactile or visceral hallucinations, rarely with depersonalization events. In subdepressive disorders, adynamia prevalent originally, vital signs appeared at the height of the disease and further on adynamia became manifest. Potentiation and evolution of senestopathy always correlated with the intensity of affective disorders. Combined therapy using low doses of the psychotropic drugs proved effective.