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The clinical, metabolic and endocrine features and the quality of life in adults with childhood-onset craniopharyngioma compared with adult-onset craniopharyngioma.

Authors
  • Kendall-Taylor, Pat
  • Jönsson, Peter J
  • Abs, Roger
  • Erfurth, Eva Marie
  • Koltowska-Häggström, Maria
  • Price, David Anthony
  • Verhelst, Johan
Type
Published Article
Journal
European journal of endocrinology / European Federation of Endocrine Societies
Publication Date
Apr 01, 2005
Volume
152
Issue
4
Pages
557–567
Identifiers
PMID: 15817911
Source
Medline
License
Unknown

Abstract

These data emphasise the generally poor state of health of patients treated for craniopharyngioma, with respect to endocrine and metabolic function, and also the markedly reduced quality of life. In addition to GHD, most patients have evidence of hypothalamic damage with associated obesity, diabetes insipidus and hypopituitarism. Adults with CO craniopharyngioma were shorter, had lower IGF-I, lower BMI, less obesity and slightly lower blood lipid levels than patients with AO craniopharyngioma.

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