Affordable Access

deepdyve-link deepdyve-link
Publisher Website

Clinical and mechanistic drivers of acute traumatic coagulopathy.

Authors
  • And 1 more
Type
Published Article
Journal
The journal of trauma and acute care surgery
Publication Date
Volume
75
Issue
1 Suppl 1
Identifiers
DOI: 10.1097/TA.0b013e31828fa43d
PMID: 23778510
Source
Medline
License
Unknown

Abstract

ATC is associated with the depletion of factors I, II, V, VII, VIII, IX, and X and is driven by the activation of the protein C system. These data provide additional mechanistic understanding of the drivers of coagulation abnormalities after injury. Further understanding of the drivers of ATC and the effects of resuscitation can guide factor-guided resuscitation and correction of coagulopathy after injury.

Statistics

Seen <100 times