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Clinical and genetic features of human germ cell cancer.

Authors
  • Dmitrovsky, E
  • Bosl, G J
  • Chaganti, R S
Type
Published Article
Journal
Cancer surveys
Publication Date
Jan 01, 1990
Volume
9
Issue
2
Pages
369–386
Identifiers
PMID: 1964627
Source
Medline
License
Unknown

Abstract

The majority of patients with disseminated germ cell cancer can be cured. However, subsets of these patients are either refractory to initial treatment or relapse after treatment. The management of these different clinical groups is reviewed. An enhanced understanding of the basic biological features of germ cell cancer may well lead to improvements in the management of this disease. Recent advances in the biological and genetic aspects of germ cell cancer which are pertinent to the behaviour of this malignancy are summarized.

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