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[Clinical effect of alprazolam and trazodone on bronchial asthmatics with anxiety disorder].

Authors
  • Haida, M
  • Itoh, K
Type
Published Article
Journal
Arerugī = [Allergy]
Publication Date
Oct 01, 1997
Volume
46
Issue
10
Pages
1058–1071
Identifiers
PMID: 9404094
Source
Medline
License
Unknown

Abstract

Onset as well as many symptoms of asthma are said to be related to autonomic dysfunction which often appear as a result of actual daily stress of the patients. Minor tranquilizers and anti-depressants are often successful in treating such symptoms, though precise effect of these drugs on asthma is not yet available, while many still hesitate to use these drug for fear of the anticholinergic effect which may hinder the efficient expectoration of sputum which could be critical during severe asthma attacks. In this study, these drugs were evaluated by the asthma score, peak flow, acetylcholine provocation test and the suppressive effect on lymphocytes. They could be beneficial in increasing the quality of asthma therapy if employed with necessary care.

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