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Clinical Application of Postmortem Magnetic Resonance Imaging in Neonates

Authors
  • Shany, Eilon
  • Marks, Kyla
  • Levitas, Aviva
  • Golan, Agneta
  • Abramsky, Ramy
  • Taragin, Benjamin H.
  • Shelef, Ilan
Type
Published Article
Journal
Neonatology
Publisher
S. Karger AG
Publication Date
Feb 05, 2021
Volume
118
Issue
1
Pages
54–63
Identifiers
DOI: 10.1159/000512923
PMID: 33550296
Source
Karger
Keywords
License
Green
External links

Abstract

Background: Recent reports advocate the use of MRI either as a substitute for postmortem examinations or for a more targeted autopsy. Methods: A full-body postmortem MRI (pMRI) of infants was performed as early as possible after death, and findings were compared to clinical premortem diagnoses. Results: Thirty-one infants were scanned during the study period. Median gestation at birth was 34 weeks (ranges: 24–43). In 3 (10%) cases, no new findings were detected. In 2 (6%), new minor findings not related to the cause of death were detected, and in 17 (55%), new minor findings related to the cause of death were detected. New major findings related to the cause of death were detected in 4 (13%) cases, and new major findings not related to the cause of death were detected in 5 (16%) cases. In 3 (10%), findings thought to alter the perceived cause of death were detected. Overall, in 23 (74%) cases, pMRI findings reinforced the clinical premortem diagnoses. Conclusions: pMRI is a culturally accepted alternative when autopsy is not performed and can either reinforce, refute, or add to premortem clinical diagnoses.

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