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Cladophialophora bantiana brain abscess in an immunocompetent patient.

Authors
  • Revankar, Sanjay G
Type
Published Article
Journal
The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie médicale / AMMI Canada
Publication Date
Jan 01, 2011
Volume
22
Issue
4
Pages
149–150
Identifiers
PMID: 23205028
Source
Medline
Keywords
License
Unknown

Abstract

Cladophialophora bantiana is a dematiaceous mold with a predilection for causing central nervous system infection, particularly in normal hosts. A case involving a 79-year-old immunocompetent woman who presented with left-sided weakness and a ring-enhancing brain lesion is reported. She underwent surgical excision, which revealed a brain abscess due to C bantiana. The patient was treated with liposomal amphotericin B for several weeks, then switched to voriconazole and flucytosine, but eventually succumbed to the infection. Therapy is not standardized for this rare mycosis, and mortality remains high, even in immunocompetent patients. Additional studies to understand the pathogenesis of this infection and to improve outcomes are needed.

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