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Circulating Exosomes and Their Role in Stroke.

Authors
  • Jafarzadeh-Esfehani, Reza1
  • Soudyab, Mohammad1
  • Parizadeh, Seyed Mostafa2
  • Jaripoor, Mohammad Ehsan3
  • Nejad, Payam Sasan4
  • Shariati, Mohammad4
  • Nabavi, Ariane Sadr3, 1
  • 1 Department of Medical Genetics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. , (Iran)
  • 2 Metabolic syndrome Research center, Mashhad University of Medical Sciences, Mashhad, Iran. , (Iran)
  • 3 Academic Center for Education, Culture and Research (ACECR)-Khorasan Razavi, Mashhad, Iran. , (Iran)
  • 4 Department of neurology, Mashhad University of Medical Sciences, Mashhad, Iran. , (Iran)
Type
Published Article
Journal
Current drug targets
Publication Date
Jan 01, 2020
Volume
21
Issue
1
Pages
89–95
Identifiers
DOI: 10.2174/1389450120666190821153557
PMID: 31433753
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Stroke is an acute neurologic disorder which can be life-threatening if left untreated or diagnosed late. Various detecting techniques including neurologic imaging of the brain by computed tomography or magnetic resonance imaging can facilitate diagnosis of stroke. However, according to the recent advances in molecular detection techniques, new diagnostic and prognostic markers have emerged. Exosomes as an extra cellar particle are one of these markers which can have useful diagnostic, prognostic, and even therapeutic impact after stroke. We have previously discussed the role of exosomes in cardiovascular disease and in the present review we focus on the most common cerebrovascular disease. The aim of the present review is summarizing the recent diagnostic role of exosomes which are specifically secreted during a stroke and can guide clinicians to better diagnosis of stroke. Copyright© Bentham Science Publishers; For any queries, please email at [email protected]

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