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Cigarette smoking and the risk of systemic lupus erythematosus, overall and by anti-double stranded DNA antibody subtype, in the Nurses' Health Study cohorts.

Authors
  • Barbhaiya, Medha1
  • Tedeschi, Sara K1
  • Lu, Bing1
  • Malspeis, Susan1
  • Kreps, David1
  • Sparks, Jeffrey A1
  • Karlson, Elizabeth W1
  • Costenbader, Karen H1
  • 1 Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Type
Published Article
Journal
Annals of the Rheumatic Diseases
Publisher
BMJ
Publication Date
Feb 01, 2018
Volume
77
Issue
2
Pages
196–202
Identifiers
DOI: 10.1136/annrheumdis-2017-211675
PMID: 28988206
Source
Medline
Keywords
License
Unknown

Abstract

Strong and specific associations of current smoking and >10 pack-years of smoking with dsDNA+ SLE were observed. This novel finding suggests smoking is involved in dsDNA+ SLE pathogenesis.

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