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Cigarette smoking and plasma nortriptyline levels.

Authors
  • Norman, T R
  • Burrows, G D
  • Maguire, K P
  • Rubinstein, G
  • Scoggins, B A
  • Davies, B
Type
Published Article
Journal
Clinical pharmacology and therapeutics
Publication Date
Apr 01, 1977
Volume
21
Issue
4
Pages
453–456
Identifiers
PMID: 849676
Source
Medline
License
Unknown

Abstract

Cigarette smoking was found to have no effect on the steady-state plasma levels of nortriptyline in a group of 22 smokers and 31 nonsmokers. Smokers achieved a mean steady-state nortriptyline concentration of 191.2 +/- 141.3 ng/ml; nonsmokers had a level of 169.3 +/- 92.4 ng/ml. Age, sex, and number of cigarettes smoked had no effect on the plasma concentrations achieved.

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