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Cigarette smoke extract stimulates interleukin-8 production in human airway epithelium and is attenuated by superoxide dismutase in vitro.

Authors
  • Mulligan, Ryan M
  • Atkinson, Carl
  • Vertegel, Alexey A
  • Reukov, Vladimir
  • Schlosser, Rodney J
Type
Published Article
Journal
American journal of rhinology & allergy
Publication Date
Jan 01, 2009
Volume
23
Issue
6
Identifiers
DOI: 10.2500/ajra.2009.23.3400
PMID: 19769800
Source
Medline
License
Unknown

Abstract

Inflammation in the airway after CSE can be blocked by SOD in this in vitro model. The ability to attenuate CSE-induced inflammation with SOD could provide a therapeutic/preventative approach for individuals with cigarette smoke exposure.

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