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[Churg-Strauss syndrome. Apropos of a clinical case].

Authors
  • Bosetto, E
  • Cervini, M
  • Delpini, A
Type
Published Article
Journal
Minerva medica
Publication Date
Jul 14, 1984
Volume
75
Issue
28-29
Pages
1739–1744
Identifiers
PMID: 6540846
Source
Medline
License
Unknown

Abstract

A case of Churg-Strauss allergic vasculitis in a 32-yr-old woman treated with phenylhydantoin for 9 yr for a form of post-traumatic epilepsy is described. The clinical overture consisted of asthmatic bronchitis, followed by the discovery of bronchopneumonic infiltrates and skin and heart lesions. Repeated biopsies revealed evidence of vasculitis involving small-calibre vessels, and extravascular infiltrates composed of eosinophilic granulocytes, lymphocytes and plasma cells, sometimes surrounding necrotic areas. Treatment of this condition is primarily based on cortisone, combined with azathioprine or cyclophosphamide in some cases.

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