Chronic periodontitis can affect the levels of potential oral cancer salivary mRNA biomarkers.
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Authors
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Cheng, Y-S L1
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Jordan, L1
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Chen, H-S2
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Kang, D3
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Oxford, L4
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Plemons, J5
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Parks, H5
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Rees, T5
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1
Department of Diagnostic Sciences, Texas A&M University College of Dentistry, Dallas, TX, USA.
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2
College of Nursing, University of Toledo, Toledo, OH, USA.
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3
Department of Surgery, Methodist Hospital, Dallas, TX, USA.
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4
Baylor University Medical Center, Dallas, TX, USA.
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5
Department of Periodontics, Texas A&M University College of Dentistry, Dallas, TX, USA.
- Type
- Published Article
- Journal
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Journal of Periodontal Research
- Publisher
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Wiley (Blackwell Publishing)
- Publication Date
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May 31, 2017
- Volume
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52
- Issue
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3
- Pages
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428–437
- Identifiers
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DOI: 10.1111/jre.12407
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PMID: 27549383
- Source
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Medline
- Keywords
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- License
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Unknown
Abstract
Salivary S100P mRNA could be a reliable biomarker for OSCC detection, regardless of the presence of chronic periodontitis. The presence of chronic periodontitis could significantly affect the levels of the other six mRNAs, and negatively influence reliability for using them as biomarkers for oral cancer detection.
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
This record was last updated on 07/07/2017 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at
https://www.ncbi.nlm.nih.gov/pubmed/27549383
