Affordable Access

deepdyve-link
Publisher Website

Chronic kidney disease predicts atrial fibrillation in patients with ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention.

Authors
  • Șerban, Răzvan Constantin1, 2
  • Șuș, Ioana1, 2
  • Lakatos, Eva Katalin1, 2
  • Demjen, Zoltan2
  • Ceamburu, Alexandru2
  • Fișcă, Paul Ciprian1, 2
  • Somkereki, Cristina1, 2
  • Hadadi, Laszlo1, 2
  • Scridon, Alina1, 3
  • 1 University of Medicine and Pharmacy of Tîrgu Mureș, Tîrgu Mureș, Romania. , (Oman)
  • 2 Emergency Institute for Cardiovascular Diseases and Transplantation, Tîrgu Mureș, Romania. , (Oman)
  • 3 Center for Advanced Medical and Pharmaceutical Research, Tîrgu Mureș, Romania. , (Oman)
Type
Published Article
Journal
Acta cardiologica
Publication Date
Dec 01, 2019
Volume
74
Issue
6
Pages
472–479
Identifiers
DOI: 10.1080/00015385.2018.1521558
PMID: 30650039
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Background: Atrial fibrillation (AF) often complicates ST-segment elevation myocardial infarction (STEMI). Predictors of AF in this setting include factors related to the acute phase of STEMI and pre-existing conditions. More recently, novel AF predictors have been identified in the general population. We aimed to assess the ability of such novel factors to predict STEMI-related AF.Methods: Data were collected from STEMI patients treated by primary PCI. Factors related to the acute phase of STEMI (Killip class, heart rate, blood pressure on admission, post-PCI TIMI flow), classic (age, hypertension, heart failure, previous myocardial infarction), and more novel (body mass index [BMI], diabetes, chronic kidney disease [CKD], chronic obstructive pulmonary disease [COPD]) AF predictors were evaluated. The ability of these novel factors to predict STEMI-related AF was assessed.Results: Of the 629 studied patients, 10.5% presented STEMI-related AF. AF patients had higher Killip class on admission (p < .0001) and lower post-PCI TIMI flow (p < .01), they were older (p < .0001) and more likely to have a history of heart failure (p = .02) and myocardial infarction (p = .04). BMI, history of diabetes and COPD were similar between patients with and without AF (all p > .05), but CKD was more common in AF patients (p < .0001). In multiple regression analysis, CKD remained a strong independent predictor of STEMI-related AF (p < .0001).Conclusion: Irrespective of other factors, CKD was associated with increased risk of STEMI-related AF. CKD could be used to identify patients who will develop AF in this setting and who would benefit from closer follow-up and more intensive prophylactic strategies.

Report this publication

Statistics

Seen <100 times